a) Drugs decreasing synthesis of uric acid
Purine – Allopurinol
Non purine- Febuxostat
b) Drugs increasing excretion of uric acid
Probenecid
Sulfinpyrazone
Benzbromarone
Lesinurad
c) Drugs increasing metabolism of uric acid
Rasburicase
Pegloticase
Q. Allopurinol prevents conversion of: ( PGI June 2004)
A) Hypoxanthine to xanthine
B) Xanthine to hypoxanthine
C) Hypoxanthine to IMP
D) Xanthine to uric acid
Ans: A, Hypoxanthine
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