Penicillin was the first antibiotic developed and used clinically which was discovered accidentally by alexander fleming. The source of penicillin is the high yielding penicillin chrysogeneum

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Moa- b lactams, a structural analogue of d alanine, inhibits transpeptidase and thus peptidoglycans synthesis..thus cell wall defficient forms are produced

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Uses -

1.  Most commonly used antibiotic in dentistry since it comes under wide spectrum classification (both aerobic and anaerobic)
2. In general medicine

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A - UTI
B - Respiratory tract infection
C - Meningitis
D - Gonorrhoea
E - Typhoid
F- Cholecystitis
G - Subacute endocarditis
H - Septicemias

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Adverse drug reactions: Hypersensitivity reaction ( ANAPHYLACTIC SHOCK ) includes ( bronchospasm, chest pain, itching, urticaria, fever, rash etc)